Meet Dr. Tom Appleton, one of our team members for Western kNOw-PAIN. He is an assistant professor of Rheumatology and clinician scientist in the Department of Medicine with a cross-appointment to the Department of Physiology and Pharmacology at Western. He is a rheumatologist with research focused on the role of synovium in the onset and progression of osteoarthritis, with expertise in innate immune inflammation, synovitis, ultrasound imaging, bioinformatics and single cell technologies, and tissue histopathology. He is investigating the mechanisms of osteoarthritis disease development and progression to identify new therapeutic targets for disease modifying osteoarthritis therapies.